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Mason Scientists Develop COVID-19 Antibody Measurement Technology to Rapidly Assess Virus Blocking Efficacy

by Tracy Mason

A cross-disciplinary team coordinated by scientists at Mason’s Center for Infectious Disease Research (CIDR), led by Yuntao Wu, Professor, School of Systems Biology, have developed the hybrid alphavirus-SARS-CoV-2 pseudovirus system that can robustly express reporter genes in cells within hours to rapidly measure neutralizing antibodies. Ha-CoV-2 pseudovirus was utilized against the COVID-19 virus and its variants including Alpha, Delta, and Omicron, as well as the currently emerging omicron BA.2 variant.

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